It's a no-win situation. However, besides prayer, it appears part of the answer is helping these countries to build stockpiles of non-perishables and livestock in anticipation of these droughts which appear to emerge on a regular basis. Also, this is also why initiatives like those the Jonas family is undertaking are so important.
Another friend is going to Ethiopia in December with Ethiopian Orphan Relief to help build a well in a remote region.
You can check out the Economist article here.
P.S. - If you want to keep up with what's happening in Africa...and the rest of the world for that matter, I highly recommend investing in a subscription to The Economist.